| NCAAF | 11/11 18:00 | 1 | Denison Big Red v Ohio Wesleyan Battling Bishops | W | 29-26 | |
| NCAAF | 11/04 17:00 | 1 | Kenyon Lords v Denison Big Red | W | 15-38 | |
| NCAAF | 10/21 19:00 | 1 | Denison Big Red v Wooster Scots | W | 35-31 | |
| NCAAF | 10/14 17:00 | 1 | Denison Big Red v Wabash Little Giants | W | 28-24 | |
| NCAAF | 10/07 17:00 | 1 | Depauw Tigers v Denison Big Red | L | 17-6 | |
| NCAAF | 09/30 18:00 | 1 | Denison Big Red v Wittenberg Tigers | L | 24-27 | |
| NCAAF | 09/23 16:00 | 1 | Hiram Terriers v Denison Big Red | W | 24-55 | |
| NCAAF | 09/16 17:00 | 1 | Oberlin Yeomen v Denison Big Red | W | 0-70 | |
| NCAAF | 09/09 23:00 | 1 | Denison Big Red v Linfield Wildcats | L | 14-28 | |
| NCAAF | 09/02 17:30 | 1 | Capital Crusaders v Denison Big Red | W | 35-45 | |
| NCAAF | 11/12 18:00 | 1 | Denison Big Red v Kenyon Lords | W | 49-12 | |
| NCAAF | 11/05 17:00 | 1 | Wooster Scots v Denison Big Red | W | 14-28 | |
| NCAAF | 10/22 16:00 | 1 | Wittenberg Tigers v Denison Big Red | W | 10-28 | |
| NCAAF | 10/15 19:00 | 1 | Denison Big Red v Hiram Terriers | W | 41-38 | |
| NCAAF | 10/08 18:00 | 1 | Ohio Wesleyan Battling Bishops v Denison Big Red | L | 41-7 | |
| NCAAF | 10/01 23:00 | 1 | Denison Big Red v Depauw Tigers | L | 13-17 | |
| NCAAF | 09/24 18:00 | 1 | Wabash Little Giants v Denison Big Red | W | 42-45 | |
| NCAAF | 09/17 17:00 | 1 | Denison Big Red v Oberlin Yeomen | W | 51-10 | |
| NCAAF | 09/10 16:00 | 1 | Hilbert Hawks v Denison Big Red | W | 0-63 | |
| NCAAF | 09/03 23:00 | 1 | Denison Big Red v Capital Crusaders | W | 48-31 | |
| NCAAF | 11/13 18:00 | 1 | Denison Big Red v Ohio Wesleyan Battling Bishops | L | 25-35 | |
| NCAAF | 11/06 17:00 | 1 | Hiram Terriers v Denison Big Red | W | 6-59 | |
| NCAAF | 10/30 17:00 | 1 | Depauw Tigers v Denison Big Red | L | 27-10 | |
| NCAAF | 10/23 19:00 | 1 | Denison Big Red v Wooster Scots | W | 52-28 | |
| NCAAF | 10/16 17:00 | 1 | Kenyon Lords v Denison Big Red | W | 7-45 | |
| NCAAF | 10/02 19:00 | 1 | Denison Big Red v Wabash Little Giants | L | 38-39 | |
| NCAAF | 09/25 23:00 | 1 | Denison Big Red v Wittenberg Tigers | W | 21-16 | |
| NCAAF | 09/18 17:00 | 1 | Oberlin Yeomen v Denison Big Red | W | 12-59 | |
| NCAAF | 09/11 19:00 | 1 |
Denison Big Red
v
Allegheny Gators
|
W | 31-0 | |
| NCAAF | 09/04 22:00 | 1 | Ohio Northern Polar Bears v Denison Big Red | L | 34-10 |