| NCAAF | 11/11 17:00 | 1 | Shepherd Rams v Mercyhurst Lakers | L | 49-25 | |
| NCAAF | 11/04 18:00 | 1 | Mercyhurst Lakers v Seton Hill Griffins | L | 0-14 | |
| NCAAF | 10/28 16:00 | 1 | California Vulcans v Mercyhurst Lakers | L | 58-19 | |
| NCAAF | 10/21 19:00 | 1 | Mercyhurst Lakers v Gannon University Golden Knights | L | 28-31 | |
| NCAAF | 10/14 16:00 | 1 | Clarion Golden Eagles v Mercyhurst Lakers | W | 35-36 | |
| NCAAF | 10/07 18:00 | 1 | Mercyhurst Lakers v Slippery Rock | L | 31-75 | |
| NCAAF | 09/30 18:00 | 1 | Edinboro Fighting Scots v Mercyhurst Lakers | L | 40-24 | |
| NCAAF | 09/23 17:00 | 1 | Mercyhurst Lakers v Iup Crimson Hawks | L | 13-30 | |
| NCAAF | 09/16 16:00 | 1 | Kutztown Golden Bears v Mercyhurst Lakers | L | 47-14 | |
| NCAAF | 09/09 22:00 | 1 | Mercyhurst Lakers v Lock Haven | W | 41-29 | |
| NCAAF | 09/01 00:00 | 1 | Ferris State v Mercyhurst Lakers | L | 54-12 | |
| NCAAF | 11/12 17:00 | 1 | Mercyhurst Lakers v Bloomsburg Huskies | L | 13-16 | |
| NCAAF | 11/12 17:00 | 1 | Mercyhurst Lakers v Shepherd Rams | - | 已取消 | |
| NCAAF | 11/05 18:00 | 1 | Seton Hill Griffins v Mercyhurst Lakers | L | 7-0 | |
| NCAAF | 10/29 16:00 | 1 | Mercyhurst Lakers v California Vulcans | L | 20-44 | |
| NCAAF | 10/22 16:00 | 1 | Gannon University Golden Knights v Mercyhurst Lakers | L | 49-14 | |
| NCAAF | 10/15 22:00 | 1 | Mercyhurst Lakers v Clarion Golden Eagles | L | 21-23 | |
| NCAAF | 10/08 22:00 | 1 | Slippery Rock v Mercyhurst Lakers | L | 31-17 | |
| NCAAF | 10/01 18:00 | 1 | Mercyhurst Lakers v Edinboro Fighting Scots | L | 13-16 | |
| NCAAF | 09/24 20:00 | 1 | Iup Crimson Hawks v Mercyhurst Lakers | L | 33-16 | |
| NCAAF | 09/17 16:00 | 1 | Mercyhurst Lakers v Kutztown Golden Bears | L | 31-50 | |
| NCAAF | 09/10 22:00 | 1 | Lock Haven v Mercyhurst Lakers | W | 7-49 | |
| NCAAF | 09/03 22:00 | 1 |
Alderson Broaddus Battlers
v
Mercyhurst Lakers
|
W | 28-45 | |
| NCAAF | 11/13 18:00 | 1 | Shippensburg Raiders v Mercyhurst Lakers | L | 17-13 | |
| NCAAF | 11/06 16:00 | 1 | Mercyhurst Lakers v Gannon University Golden Knights | W | 24-13 | |
| NCAAF | 10/30 16:00 | 1 | Clarion Golden Eagles v Mercyhurst Lakers | W | 20-38 | |
| NCAAF | 10/23 16:00 | 1 | Mercyhurst Lakers v Slippery Rock | L | 17-20 | |
| NCAAF | 10/16 16:00 | 1 | Edinboro Fighting Scots v Mercyhurst Lakers | W | 20-27 | |
| NCAAF | 10/09 16:00 | 1 | Mercyhurst Lakers v Seton Hill Griffins | L | 17-19 | |
| NCAAF | 10/02 19:00 | 1 | California Vulcans v Mercyhurst Lakers | L | 37-0 |